Ultrastructural analysis of synapses primary somatosensory cortex and anterior cortical nucleus of rats with absence epilepsy

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Doklady Bashkirskogo Universiteta. 2016. Volume 1. No. 2. pp. 287-291.

Authors

Fedorova A. M.*
Bashkir State University
Russia, 450076 Ufa, Zaki Validi 32
Sadrtdinova I. I.
Bashkir State University
Russia, 450076 Ufa, Zaki Validi 32
Khismatullina Z. R.
Bashkir State University
Russia, 450076 Ufa, Zaki Validi 32
Kalimullina L. B.
Bashkir State University
Russia, 450076 Ufa, Zaki Validi 32

Abstract

The quantitative and ultrastructural analysis of the synapses are studied of the fifth layer of the primary somatosensory cortex (PSC) and the anterior cortical nucleus amygdala (CoA) brain rats WAG / Rij line. Rats WAG / Rij line is a model of human absence epilepsy. we identified different types of synapses: axo-somatic, axo-dendritic, axo-spiny, dendrodendritic and axo-axonal in the PSC and the CoA. Analyzed: the density of synapses (on 100 mkm2), the relative frequency of occurrence of asymmetric, symmetric, perforated and invaginated synapse size and shape of synaptic vesicles.

Keywords

  • epilepsy
  • rats
  • synapses
  • the primary somatosensory cortex
  • amygdala
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