Studying kinetics of release medicinal substances from chitosan films
Doklady Bashkirskogo Universiteta. 2021. Volume 6. No. 1. pp. 8-13.
Authors
Shurshina A. S.
Bashkir State University
32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
Lazdina M. Yu.*
Bashkir State University
32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
*E-mail: mashalazdina@mail.ru
Abstract
The kinetics of controlled release of medicinal substances from chitosan films has been investigated. Correlation between values of coefficients diffusion and shares of medicinal substance connected with a polymeric chain has been established. It was shown that the greater proportion of the medicinal substance connected with a polymeric chain, the lower the value of diffusion coefficients and the index defining process of diffusion in the chitosan films, and the slower transport of medicinal substance from a polymeric matrix.
Keywords
- хитозан
- лекарственное вещество
- диффузия
- аномальный характер