Morphological changes in the ovaries at absence epilepsy

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Doklady Bashkirskogo Universiteta. 2020. Volume 5. No. 1. pp. 13-16.

Authors

Zalilova S. R.*
Bashkir State University
32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia
Sadrtdinova I. I.
Bashkir State University
32 Zaki Validi Street, 450076 Ufa, Republic of Bashkortostan, Russia

Abstract

The work is devoted to the study of morphometric parameters of rat’s ovaries in normal state and in case of absence epilepsy. For the first time a comparative analysis of the ovaries of female Wistar and WAG/Rij rats, which represent a genetic model of generalized absence epilepsy in humans has been performe. It was experimentally found that in female WAG/Rij rats the structural and morphometric changes are observed, which may be associated both with impaired endocrine function of rat ovaries, and with the process of folliculogenesis.

Keywords

  • absence epilepsy
  • WAG/Rij rats
  • ovary
  • follicle
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