Study of the structure of rats IgG Fc fragments exposing neo-epitopes recognized by the regulatory rheumatoid factor

Doklady Bashkirskogo Universiteta. 2018. Volume 3. No. 4. pp. 456-459.

Authors


Sidorov A.*
Udmurt State University
1 Universitetskaya Street, 426034 Izhevsk, Udmurt Republic, Russia
Beduleva L.
Udmurt State University
1 Universitetskaya Street, 426034 Izhevsk, Udmurt Republic, Russia
Irina M.
Udmurt State University
1 Universitetskaya Street, 426034 Izhevsk, Udmurt Republic, Russia
Terentiev A.
Udmurt State University
1 Universitetskaya Street, 426034 Izhevsk, Udmurt Republic, Russia
Menshikov I.
Udmurt State University
1 Universitetskaya Street, 426034 Izhevsk, Udmurt Republic, Russia

Abstract


It was found that the Fc fragments of rat IgG exposing neo-epitopes recognized by the regulatory rheumatoid factor are aggregates formed due to hydrophobic interactions.

Keywords


  • Fc fragments rats IgG
  • regulatory rheumatoid factor
  • neo-epitope
  • aggregates