Association study of IL8 and IL10 genes polymorphisms in gastric cancer development

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Doklady Bashkirskogo Universiteta. 2017. Volume 2. No. 1. pp. 41-47.

Authors

Nurgalieva A. Kh.*
Bashkir State University
32 Zaki Validi Street, 450074 Ufa, Republic of Bashkortostan, Russia
Yusupova L. F.
Bashkir State University
32 Zaki Validi Street, 450074 Ufa, Republic of Bashkortostan, Russia
Khusnutdinova E. K.
Bashkir State University; Institute of Biochemistry and Genetics, Russian Academy of Sciences
32 Zaki Validi Street, 450074 Ufa, Republic of Bashkortostan, Russia; 71 Prospekt Oktyabrya, 450075 Ufa, Republic of Bashkortostan, Russia

Abstract

An associative study of cytokine gene polymorphisms of interleukin-8 IL8 (rs4073) and interleukin-10 IL10 (rs1800872) in gastric cancer patients and healthy donors from the Bashkortostan Republic. There were been found associations of a polymorphic variant rs1800872 of IL10 gene with the risk of gastric cancer in Russians and Tatars.

Keywords

  • gastric cancer
  • cytokine genes
  • polymorphisms
  • association
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